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This article describes the context in which 3,4-methylenedioxyamphetamine MDA3,4-methylenedioxymethamphetamine MDMA and other mescaline-like compounds were explored as hallucinogens for military and intelligence purposes from the s to the s. Germans first tested mescaline as a "truth drug" in a military context.
In the s, the United States military started testing hallucinogenic substances as truth drugs for interrogation and behavior manipulation. After tests carried out using mescaline and other drugs insome derivatives of mescaline were synthesized by the Army for the exploration of possible "speech-inducing" effects.
During tests with other derivatives 3,4-dimethoxyphenethylamine DMA3,4-methylenedioxyphenethylamine MDPEAMDA inan unwitting patient died in these tests, which was kept secret from the public. Research was interrupted and toxicological animal testing procedures were initiated. Inthe military changed focus to lysergic acid diethylamide LSDbut some interest in mescaline-like compounds remained for their ability to change mood and habit without interfering with cognition and sensory perception.
Based on the known documents, it remains unclear but probable whether any of the mescaline derivatives tested were being used operationally. Please enable it to take advantage of the complete set of features! Clipboard, Search History, and several other advanced features are temporarily unavailable.
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of items displayed: 5 10 15 20 50 Create RSS Cancel. RSS Link Copy. Full text links Cite Display options Display options. Abstract This article describes the context in which 3,4-methylenedioxyamphetamine MDA3,4-methylenedioxymethamphetamine MDMA and other mescaline-like compounds were explored as hallucinogens for military and intelligence purposes from the s to the s. Dunlap LE, et al. ACS Chem Neurosci. Epub Jul Differences in the stimulus properties of 3,4-methylenedioxyamphetamine and 3,4- methylenedioxymethamphetamine in animals trained to discriminate hallucinogens from saline.
Callahan PM, et al. J Pharmacol Exp Ther. PMID: Baker LE, et al. Pharmacol Biochem Behav. Optical isomer analysis of 3,4-methylene-dioxyamphetamine analogues and their stereoselective disposition in rats. Matsushima K, et al. J Anal Toxicol. Monks TJ, et al. Ther Drug Monit. PMID: Review. See all similar articles. Agin-Liebes G, et al. Dark Classics in Chemical Neuroscience: 3,4-Methylenedioxymethamphetamine. Publication types Review Actions. Animals Actions.
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